Preclinical Pharmacokinetic Studies

• PK Studies on Different Species and Administration Routes
  • Mouse/Rat/Guinea Pig/Rabbit/Dog/Pig
  • Intravenous / Subcutaneous / Transdermal / Intramuscular / Intraperitoneal / Oral / Intranasal / Ophthalmic
• Organizational Distribution Research
• Excretion Research

Preclinical Pharmacokinetics (and Toxicokinetics) Studies (TK)

In vitro drug metabolism studies

Drug-Drug Interaction (DDI) Assessment

Induction and inhibition of drug-metabolizing enzymes, as well as enzyme phenotype confirmation techniques

Material Balance (Isotopically Labeled Compounds / Non-Isotopically Labeled Compounds)

Identification and Abundance Assessment of Innovative Drug Metabolites

Caco-2 cell monolayer model

Plasma protein binding rate

Small chemical molecules (LC-MS/MS and ICP-MS analysis techniques for liquid chromatography-mass spectrometry)

• Pharmacokinetic Study (PK)
• Pharmacodynamic Studies (PD)
• Formulation Consistency Evaluation and Human Bioequivalence (BE) Studies

Biopolymers (ELISA, MSD, time-resolved fluorescence, CLIA, immunofluorescence, qPCR, etc.)

• Pharmacokinetic Study (PK)
• Pharmacodynamic Studies (PD)
• Immunogenicity Study (ADA)
• Neutralizing Antibody Assay (Nab)
• Biomarker Research
• Toxicokinetic Studies (TK)

Biological sample storage (capacity up to 2 million+)

• Different matrices (plasma, serum, urine, tissue, etc.)
• Different temperatures (-80 ^O C ~ 4 ^O C)
• 24/7 Online Monitoring

Genotoxic impurities

Therapeutic Drug Monitoring (TDM)

Metal Element Detection

Illegal Additions in Traditional Chinese Medicine and Health Supplements

Analysis and Testing of Active Compounds in Herbal Medicines

Drug Addiction Screening

Doping Control